Part 1| ADNeT Screening and Trials Protocol: Measures and Interpretation
During the first part of the webinar, Dr Jo Robertson provides an overview of the measures administered by ADNeT,’s Screening and Trials initiative, together with notes on their interpretation.
Part 2 | Interpretation of Amyloid PET Reports
Amyloid PET is an accurate test for the detection of amyloid beta (Aβ) plaques demonstrating more than 90% concurrence with a post-mortem classification of moderate or frequent Aβ plaque deposition. Importantly, neuropathological criteria also require the presence of tau neurofibrillary tangles to confirm a neuropathological diagnosis of Alzheimer’s disease (AD). However even then, individuals who meet neuropathological criteria for AD may be cognitively intact.
In Part 2 of this webinar, Prof. Rowe will discuss through case-based learning the clinical implications of a positive and negative Amyloid PET scan. His presentation will also highlight the importance of considering the level of brain amyloid present on the scan, the age and clinical status of the patient as well as the likelihood of co-existent other brain pathology when deciding if AD is the predominant cause of cognitive impairment in an individual.